Transfer of Premelanosomes into the Keratinizing Cells of Albino Hair Follicle

1The terminology used in this report is the one adopted by the 5th International Congress of Pigment Cell Biology held at the New York Academy of Sciences in 1961. into the differentiating medullary and cortical cells of the hair. A number of genes affect hair color in mammals by controlling both the synthesis and transfer of pigment. Investigations of the melanocytes of the hair follicle with the electron microscope have demonstrated that the formation and structure of pigment granules differ according to the genotype of the animal (1, 2, 6, 8). In all pigmented genotypes, the synthesis of pigment granules begins with the production of a premelanosome which is a matrix